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How to grow a healthy lab

A healthy research environment is fundamental to good science. However, this is an aspect that is rarely discussed. That’s partly because a lab’s “health” is complex and difficult to assess – it is the product of a whole host of factors, such as inclusivity, communication, expectations …

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Replication Study: Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma

As part of the “Reproducibility Project: Cancer Biology”, a Registered Report (Repass et al., 2016) was published in 2016, that described how to replicate an experiment from the paper “Fusobacterium nucleatuminfection is prevalent in human colorectal carcinoma” (Castellarin et al., 2012). Here, the “Reproducibility Project: Cancer …

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PREPARE (Planning Research and Experimental Procedures on Animals: Recommendations for Excellence) Guidelines

As part of ongoing efforts to reduce waste and increase the reproducibility of animal research and testing, a group of experts led by the Secretary of Norecopa has produced a set of guidelines for planning animal experiments: The PREPARE guidelines for planning animal experiments complement the …

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Zebrafish (Danio rerio) Environmental Summary, Aquatic Resources Program, Boston Children’s Hospital 2017

Environmental and housing conditions experienced by laboratory animals exert profound effects on their biology, physiology, and behavior. These parameters are important and often overlooked sources of potential variation in experiments. To that end, Christian Lawrence and colleagues provide a summary of the environmental conditions in zebrafish …

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