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New PAASP publication: ‘The reproducibility crisis in preclinical research – lessons to learn from clinical research’

In this article, Laia Pedro-Roig and Christoph Emmerich discuss ways and measures how preclinical research and development (especially in its confirmatory phase) would benefit from adapting some of the internationally accepted quality standards and principles used in clinical research. In contrast to clinical research, with generally …

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PAASP is part of the BMBF-funded GOT-IT (‘Guidelines On Target Validation for Innovative Therapeutics’) Project

Medical progress and continued supply of innovative medicines can only be guaranteed by continuous research and development of new active drugs and therapeutics. The most important starting point for the identification of new drugs are disease-modifying targets. Thus, the proper validation of pharmaceutically relevant targets based …

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