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Newsletter May 2020

NEWS The Global Preclinical Data Forum announces the 2020 Negative Data Prize – Read more Dr. Thomas Steckler joins the PAASP Advisory Board – Read more PAASP welcomes Dr. Renza Roncarati as the newest member of the global PAASP Network – Read more PLOS launches reserach data survey – Read more …

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Additional reads in May 2020

SuperPlots: Communicating reproducibility and variability in cell biology Against pandemic research exceptionalism Pseudoscience and COVID-19 — we’ve had enough already Spin in Scientific Publications: A Frequent Detrimental Research Practice Pseudoscience and COVID-19 — we’ve had enough already Coronavirus in context: tracks positive and negative citations …

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Beauty is not everything

Being able to trust the experimental data is critical for experimental research. This is certainly also true for Western Blotting as one of the most commonly used methods in cell biology laboratories due to its high specificity and sensitivity.Hence there is a critical need for comprehensive …

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Systematic review of guidelines for internal validity in the design, conduct and analysis of preclinical biomedical experiments involving laboratory animals

Several initiatives have set out to increase transparency and internal validity of preclinical studies. While many of the points raised in these various guidelines are identical or similar, they differ in detail and rigour. Most of them focus on reporting, only few of them cover the …

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Variability in the analysis of a single neuroimaging dataset by many teams

To test the reproducibility and robustness of results obtained in the neuroimaging field, 70 independent teams of neuroimaging experts from across the globe were asked to analyze and interpret the same functional magnetic resonance imaging dataset.The authors found that no two teams chose identical workflows to …

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Covid-19 and the PPV

There has been a lot in the news recently about using antibody tests to detect people who have had Covid-19 and who might therefore be immune to further infection (this remains to be proven). Despite the relatively good performance of many of the proposed antibody tests, …

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