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Replication Study: Intestinal inflammation targets cancer-inducing activity of the microbiota

As part of the Reproducibility Project: Cancer Biology, this report describes the attempt to replicate critical experiments from the paper “Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota” (Arthur et al., 2012). In agreement with the original study, the authors did not observe any changes on …

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Researcher Requests for Inappropriate Analysis and Reporting: A U.S. Survey of Consulting Biostatisticians

In this report, Wang and colleagues present the results of a national survey of nearly 400 consulting statisticians about requests from investigators to engage in inappropriate statistical practices. The four most frequently reported inappropriate requests were (in order of frequency): a) removing or altering some data …

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Reproducibility of Molecular Phenotypes after Long-Term Differentiation to Human iPSC-Derived Neurons: A Multi-Site Omics Study

At the presentation of the ECNP Negative Data Award (see above), there was an interesting point made by one of the presenters – about the important role of large multi-national multi-lab collaboration projects for the scientific progress. More specifically, it was emphasized that initiatives such as …

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