We have evaluated blinding procedures at 12 academic labs, 7 contract research organisations (CROs), and 4 industrial pharmacology labs and obtained access to information about 72 independent studies. Results of our analysis are presented in the Figure below: These results suggest that simply stating that studies were blinded may not always be sufficient, although the sample size of our analysis is limited and might be biased. Furthermore, description of the blinding procedure should explicitly indicate which parts of the experiment were blinded (e.g. administration of treatment, data collection, analysis, etc.) and whether the blinding procedure was part of a more general effort that also included randomization. As our database grows, this analysis will be updated. If you are interested to learn more or would like to receive updates, please let us know.
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