In: Featured Article
Is N-Hacking Ever OK?
December 22, 2023The consequences of collecting more data in pursuit of statistical significanceYou probably have encountered this: you did an experiment, observed a…
Read MoreHow can Core Facilities support best research practices?
December 20, 2021Core Facilities (CFs) are a major player within the research landscape since they provide essential infrastructures, experimental support and knowledge to…
Read MorePEERS – An Open Science “Platform for the Exchange of Experimental Research Standards” in Biomedicine
November 3, 2021Do I need to consider the sex of the animals for my study? Is the background noise level likely to vary?…
Read MoreStandardized and reproducible measurement of decision-making in mice
June 16, 2021Reproducibility of data has never been more at the forefront of scientific endeavour than now. In their latest contribution, the International…
Read MoreImpact of tumour heterogeneity and tissue sampling for genetic mutation testing: a systematic review and post hoc analysis
August 17, 2020Staff at QED Biomedical Ltd have conducted research to demonstrate how sample bias in patient- derived tumour tissue samples with somatic…
Read MoreImproving quality of preclinical academic research through auditing: A feasibility study
March 31, 2020Commentary provided by Claudia Kurreck (Department of Experimental Neurology, Charité -Universitätsmedizin Berlin, Germany) The performance of audits and assessments is always a…
Read MoreReproducibility of Molecular Phenotypes after Long-Term Differentiation to Human iPSC-Derived Neurons: A Multi-Site Omics Study
November 17, 2018At the presentation of the ECNP Negative Data Award (see above), there was an interesting point made by one of the…
Read MoreWhat exactly is N in cell culture and animal experiments?
June 6, 2018“Accurate Design of in vitro experiments – Why does it matter?” was the name of a previous post (LINK) from our…
Read MoreReproducibility of preclinical animal research improves with heterogeneity of study samples
February 27, 2018Pre-clinical animal research is typically based on single-laboratory studies conducted under highly standardized conditions. However, a new study published by Bernhard…
Read MoreDevelopment of an information sharing platform – Pharma shares unpublished results
May 22, 2016F1000 Research has published an article entitled “In search of the mechanisms of ketamine’s antidepressant effects: How robust is the evidence…
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