Anton Bespalov

November 22, 2019

Estimation vs Hypothesis-Testing

As some of our readers may know, the PAASP team was involved in the “Negative results Award” project that took place in 2018. One important lesson for us was that any discussion about negative (or null) results should start with a decision whether results are really …

November 22, 2019

by Anton Bespalov

ARRIVE 2.0

A long-awaited revision of the ARRIVE guidelines has finally been published (The ARRIVE guidelines 2019).What impact can we expect from ARRIVE 2.0? At the very least, we hope that the Nature journals will update their life sciences checklist, which will certainly have an impact. As an example, let’s …

December 20, 2018

by Anton Bespalov

Power analysis for two-sided t-test

The example below does not require any additional R packages to be installed (i.e. runs with the basic R installation).This example conducts power analysis for an expected difference between means equal to 2 with the standard deviation of 1 at a range of alpha and beta …