Parent for different guidelines
For all different stakeholders within the scientific community (researchers, reviewers, editors, policymakers, funding agencies, journalists, and the general public) it is important that scientific claims are as accurate as possible. However, there is increasing evidence questioning the robustness and accuracy of social and biomedical research outcomes. …
There is a growing concern that flawed statistics and deficient reproducibility in biomedical studies results in an unethical waste of animals in research. This review by Romain-Daniel Gosselin aims to provide guidelines in biostatistics for researchers, based on frequently observed mistakes, misuses and misconceptions as well …
The ARRIVE guidelines are widely endorsed but compliance is limited. The IICARus Collaboration group sought to determine whether journal-requested completion of an ARRIVE checklist improves full compliance with the guidelines. In a randomised controlled trial, manuscripts reporting in vivo animal research submitted to PLOS ONE (March-June …
Unambiguous identification of antibodies, cell lines and organisms around the globe: A call for the Research Resource ID The reproducibility crisis affecting different research areas is widely discussed, and – without any doubt- the underlying causes are very complex. It is also clear that there is …
The International Council for Laboratory Animal Science (ICLAS) has recently published Harmonized Animal Research Reporting Principles (HARRP), the first step of a unified approach by ICLAS to improve research reporting standards worldwide. ICLAS was established in 1956, under the auspices of UNESCO with the goal of …
For decades, scientists and organizations have expressed concerns about the quality of animal research reporting. These concerns and efforts to establish better standards along with guidelines for researchers have gained more attention and importance lately given the ongoing discussion about a “reproducibility crisis” in biomedical research. …
The PREPARE (Planning Research and Experimental Procedures on Animals: Recommendations for Excellence) guidelines were published in 2017 to provide overarching guidance on how to plan animal experiments. This comprehensive set consists of 15 topics to cover literally all aspects of animal research. A detailed checklist is incredibly …
These articles are presenting ideas on how to improve experiments. Howells, DW et al. 2014. “Bringing rigour to translational medicine.” Nature Reviews Neurology 10, 37–43 Kwon, BK et al. 2011. “A Grading System To Evaluate Objectively the Strength of Pre-Clinical Data of Acute Neuroprotective Therapies for …
