In: Tools and Resources

Assessment of benefit of animal research
December 19, 2025

Unless and until we have validated non-animal alternative methods available for routine use, the involvement of animals in research is required…

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Valuable resource: Sex as a biological variable
December 19, 2025

Several years ago, we were part of an NIH-funded consortium that developed training materials to provide practical guidance to preclinical researchers…

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DRIVER: Design and reporting of in vitro experiments
December 18, 2025

The RIVER project – originally standing for Reporting In Vitro Experiments Responsibly – was launched in order to improve reporting standards…

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To ARRIVE or not: Ticking (wrong) boxes
December 17, 2025

Every now and then we read publications stating that experiments “were conducted according to ARRIVE guidelines”. In most cases, such statements suggest that…

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Intentional misconduct or too busy to oversee the lab? 
December 23, 2024

The recent scientific misconduct in the laboratories of Eliezer Masliah is not the first such case and will unfortunately most likely…

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A qualitative study of the barriers to using blinding in in vivo experiments and suggestions for improvement
December 22, 2023

In animal experiments, blinding is a methodological strategy to reduce the risk that scientists, animal care staff, or other staff involved…

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Advanced methods and implementations for the meta-analyses of animal models: Current practices and future recommendations
December 22, 2023

Meta-analytic techniques have been widely used to synthesize data from animal models of human diseases and conditions, but these analyses often…

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Designing, conducting, and reporting reproducible animal experiments
December 22, 2023

In this review, Emma Wilson and colleagues aim to engage researchers in the discussion on research reproducibility and to provide the…

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Good Research Practice online course
December 22, 2023

We are thrilled to announce that we have completed the development of our Good Research Practice online course and it will…

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Sex as a biological variable in preclinical research:  Unforeseen and abused degree of freedom 
December 21, 2023

In many fields of biomedical research, in vivo studies traditionally involved the use of male subjects.  The situation recently started to…

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