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MANILA – A web tool for designing reproducible and transparent preclinical intervention studies

Teemu D. Laajala1,21: University of Turku, Turku (Finland), Department of Mathematics and Statistics2: University of Colorado, Denver (CO, US), Anschutz Medical Campus, Department of Pharmacology MANILA (MAtched ANimaL Analysis) is a novel web-based tool that leverages predictive baseline variables and incorporates complex baseline characteristics for allocating treatment …

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Collection of resources for the use of R in study design and analysis

In the recent report on „Digital tools and services to support research replicability and verifiability”, Caroline Skirrow and Markus Munafó have argued that “publication of analysis scripts can help to improve transparency of data analytic methods, allowing greater replicability and verifiability of scientific results”. We strongly support the …

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Simple changes of individual studies can improve the reproducibility of the biomedical scientific process as a whole

Today, the probability of successfully publishing negative/null results in biomedical research is lower than that for positive results. For instance, negative results repeatedly remain in lab books or drawers, or are not being published because they are rejected by scientific journals. These seemingly positive results then …

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