In: Commentaries
“Publication of negative/null results discussed at NIH”
November 2, 2022NINDS Office of Research Quality has presented a proposal on how to address the publication bias. It can be watched HERE (starts at…
Read More“The customer is king!”
November 2, 2022Once during our vacation in Greece, our children asked for ice cream after having dinner. When the waiter was asked about…
Read More“Hold your horses!”
November 2, 2022Risk of Alzheimer’s disease nearly doubles in older adults with Covid-19! Like many of you, several weeks ago we have also…
Read More“The Steal syndrome – or the FDA Modernization Act to end animal testing requirement passes U.S. Senate”
November 2, 2022On September 29, 2022, the U.S. Senate passed the FDA Modernization Act 2.0, S.5002, by unanimous consent. While it is unclear…
Read MoreArchimedes‘ fulcrum and the “reproducibility” debate
June 16, 2022We like to cite Dorothy Bishop who wrote several years ago: “We know how to formulate and test hypotheses in controlled…
Read More“Serial de-risking”: Quod licet Iovi non licet bovi?
June 16, 2022When it comes to novel therapies, positive data has justifiably more value than negative or null data. Indeed, positive data promises…
Read MorePre-study odds
March 14, 2022One of the key themes in the 2005 seminal paper by John Ioannidis “Why most published research findings are false” is…
Read MorePreparing for a journey
February 27, 2022Recently, I went on a trip to a nice hotel with a swimming pool. Upon arrival, standing in the modern room…
Read MoreThe “from-quality-to-system” pendulum
December 20, 2021by Anton Bespalov and Anja Gilis In the dialectics world of the German philosopher Georg Hegel, quantitative changes transform into qualitative…
Read MoreOf peer review and data sharing
November 3, 2021We (preclinical) learn from the Big Brother (clinical). For example, they recognize the risks of bias in study design, conduct and…
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