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Is N-Hacking ever OK?

It has been proposed repeatedly that adding samples based on results of initial experiments is a form of p-hacking (see e.g. new Instructions to Authors of journals of the Am Soc Exp Pharmacol Ther). While these recommendations were based on sound theoretical considerations, Pamela Rainagel from San Diego …

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Invited Commentary: Qeios – from a powerful writing tool to an immidiate Open Access platform

By Gabriele MarinelloCo-founder, Qeios We have just started with Qeios the path towards the necessary revolution in research production, quality check and sharing.We have built an astonishingly simple integrated system which combines those three distinct phases of the research life-cycle. Besides being freely accessible to everyone, simpler and …

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MANILA – A web tool for designing reproducible and transparent preclinical intervention studies

Teemu D. Laajala1,21: University of Turku, Turku (Finland), Department of Mathematics and Statistics2: University of Colorado, Denver (CO, US), Anschutz Medical Campus, Department of Pharmacology MANILA (MAtched ANimaL Analysis) is a novel web-based tool that leverages predictive baseline variables and incorporates complex baseline characteristics for allocating treatment …

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