By: Christoph Emmerich

Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials
November 22, 2019

Use of high-quality tools is an essential element of Good Research Practice. Like for many other aspects, “high quality” is a…

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Toward Good In Vitro Reporting Standards
November 22, 2019

Many areas of biomedical science have developed reporting standards and checklists to support the adequate reporting of scientific efforts, but in…

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Reproducible and Transparent Research Practices in Published Neurology Research
November 22, 2019

The objective of this study by Rauh et al. was to evaluate the nature and extent of reproducible and transparent research…

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Four erroneous beliefs thwarting more trustworthy research
November 22, 2019

A range of problems currently undermines public trust in biomedical research. In this article, Mark Yarborough and colleagues discuss four erroneous…

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Laboratory mice born to wild mice have natural microbiota and model human immune responses
November 22, 2019

Mice can be a valuable model for early biomedical research, but many of the drugs that demonstrate promising results in these…

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Presentation of the newly developed Guidelines On Target Validation for Innovative Therapeutics (GOT-IT)
November 22, 2019

Representing the GOT-IT Team, Christoph Emmerich presented the GOT-IT Guidelines at the “BMBF Vernetzungstreffen zur Nationalen Wirkstoffinitiative” on the 8th of October…

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License to Kill – From Killer Experiments and Synthetic Lethality
August 12, 2019

The Maternal Embryonic Leucine zipper Kinase (MELK) is an interesting enzyme:In 2005, MELK was first implicated in cancer by finding elevated…

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Accurate design of in vitro experiments – why does it matter?
August 24, 2016

Good statistical design is a key aspect of meaningful research. Elements such as data robustness, randomization and blinding are widely recognized…

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