We have discussed this topic several times before (HERE and HERE). There seems to be a growing understanding that, when reporting an experiment’s results, one should state clearly what experimental units (biological replicates) are included, and, when applicable, distinguish them from technical replicates. In discussing this topic with …
By Dr. Michael Lauer (NIH) Link to web page
Use of high-quality tools is an essential element of Good Research Practice. Like for many other aspects, “high quality” is a relative term suggesting that the tools are fit-for-purpose according to the best information available today.A recent paper by Lin and colleagues illustrates that, with the …
Many areas of biomedical science have developed reporting standards and checklists to support the adequate reporting of scientific efforts, but in vitro research still has no generally accepted criteria. In this article, the authors discuss ‘focus points’ of in vitro research, ensuring that the scientific community …
A range of problems currently undermines public trust in biomedical research. In this article, Mark Yarborough and colleagues discuss four erroneous beliefs that may prevent the biomedical research community from recognizing the need to focus on deserving this trust, and which can act as powerful barriers …
Representing the GOT-IT Team, Christoph Emmerich presented the GOT-IT Guidelines at the “BMBF Vernetzungstreffen zur Nationalen Wirkstoffinitiative” on the 8th of October 2019, which was attended by academic PIs, industry representatives, officials from the Federal Ministry of Education and Research and members of the German Parliament.Furthermore, PAASP …
The Maternal Embryonic Leucine zipper Kinase (MELK) is an interesting enzyme:In 2005, MELK was first implicated in cancer by finding elevated levels of MELK RNA expression in many human tumors (REF1). Since the initial article, another 32 articles have been published that specifically implicate MELK as …
