As some of our readers may know, the PAASP team was involved in the “Negative results Award” project that took place…

The Maternal Embryonic Leucine zipper Kinase (MELK) is an interesting enzyme:In 2005, MELK was first implicated in cancer by finding elevated…

A team of researchers led by Eleftherios P. Diamandis at the University of Toronto set out to discover novel serological markers…

It has been more than 10 years since two seminal papers by Ludolph et al (2007) and Scott et al (2008) have introduced recommendations for…

The importance of reporting small details and making well-informed decisions about which information to include for each experimental parameter/factor in scientific…

Amyloid beta (Aß) accumulation in the brain is regarded as one of the histopathological hallmarks of Alzheimer’s disease. However, Aß build-up…

Listeria monocytogenes is an intracellular pathogen and the causative agent of the food-borne disease listeriosis. This disease primarily affects pregnant women,…

Preclinical in vivo scientists often have to deal with a very interesting situation: Imagine we design a study to demonstrate that…

As part of the “Reproducibility Project: Cancer Biology”, a Registered Report (Repass et al., 2016) was published in 2016, that described…

“When she arrived, I gave her a data set of a self-funded, failed study which had null results (it was a…