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Heads I win, tails you lose

Preclinical in vivo scientists often have to deal with a very interesting situation: Imagine we design a study to demonstrate that “our” drug can exert certain pharmacodynamic activity. As it unfortunately happens rather often, we design this study to include only one dose of our drug …

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The Birthday Paradox

In biomedical research, dealing with probabilities is part of the daily routine for many scientists, independently of their specific research area. Statistics and probability calculations are important during the design phase of experiments (e.g., for group size calculation and power estimations), as well as during the …

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