In: Literature
Findings of a retrospective, controlled cohort study of the impact of a change in Nature journals’ editorial policy for life sciences research on the completeness of reporting study design and execution.
November 10, 2017Poor replication of in vivo and in vitro biomedical studies has been reported and this can be linked in many cases…
Read MoreAbandon Statistical Significance
November 10, 2017In science publishing and many areas of research, we have reached a ‘binary decision rule’ in which any result is first…
Read MoreModeling science trustworthiness under publish or perish pressure
November 10, 2017A new mathematical model by David R. Grimes, Chris T. Bauch and John P.A. Ioannidis suggests that a bias by journals…
Read MoreLiving systematic review: 1. Introduction – the why, what, when, and how
September 28, 2017Systematic reviews are difficult to keep up to date, but failure to do can lead to a decay in review currency,…
Read MoreHow To Survive the Medical Misinformation Mess
September 28, 2017In this article, John P. A. Ioannidis and colleagues discuss the problem of having much unreliable and non-useful published medical research….
Read MoreStandardized mean differences cause funnel plot distortion in publication bias assessments
September 28, 2017Meta-analysis is a complex statistical method which involves synthesis of data from relevant studies to devise an effect size or a…
Read MoreMore interesting stories in August 2017
September 1, 2017A long journey to reproducible results Don’t run biomedical science as a business Metrology is key to reproducing results Do our…
Read MoreWhen Null Hypothesis Significance Testing Is Unsuitable for Research: A Reassessment
September 1, 2017Null hypothesis significance testing (NHST) is linked to several shortcomings that are likely contributing factors behind the widely debated replication crisis…
Read MoreEnhancing the usability of systematic reviews by improving the consideration and description of interventions
September 1, 2017The importance of adequate intervention descriptions in minimizing research waste and increasing reproducibility rates has gained attention in the past few…
Read MorePower-up: a reanalysis of ‘power failure’ in neuroscience using mixture modelling
September 1, 2017In 2013, a paper by Katherine S. Button called ‘Power failure: why small sample size undermines the reliability of neuroscience’ was…
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